GARN, Game Algorithms for RNa 3D sampling

Example of RNA structure

GARN is a software to compute a sampling of RNA 3D structure from a secondary structure.

GARN can thus be a suitable starting point for large RNA molecular modelling and experimental structure resolution. The reference below is related to the first version of GARN. Now you can also dowload the new version of GARN: GARN2. Although GARN2 benefits from the first version of GARN, some of the main features of GARN2 are very different. Notably, GARN2 is able to extract from the sampling two best possible structures close to the native. GARN2 is also much faster than the previous version.

GARN: Sampling RNA 3D Structure Space with Game Theory and Knowledge-Based Scoring Strategies Boudard M, Bernauer J, Barth D, Cohen J, Denise A (2015) GARN: Sampling RNA 3D Structure Space with Game Theory and Knowledge-Based Scoring Strategies. PLoS ONE 10(8): e0136444. doi: 10.1371/journal.pone.0136444x

Support